
SUPERNOVA
Two-phase peeling and post-treatment cream
The new era of needle-free cell regeneration and biorevitalization, for all skin types and all areas of the face and body.
Scientific research at the service of aesthetic medicine
At Supernova, scientific progress is entirely at the service of people's well-being; through a bold vision and increasingly challenging goals, we are committed to becoming the global leader in patented medical devices for aesthetic medicine. R&D is the heart of Supernova; in our in-house laboratories, we formulate innovative and effective products that meet the most complex needs of healthcare professionals, offering effective solutions to patients' key concerns. Rigorous studies and scientific tests conducted by our team allow us to evaluate the efficacy and biocompatibility of medical devices, offering the market only safe products with undisputed added value
The value chain
We can manage the entire medical device production process: from formulation to
production, in compliance with current regulations.
The value chain
We can manage the entire medical device production process: from formulation to
production, in compliance with current regulations.

Our Pillars
We create innovative, effective, and safe medical devices that meet the real needs of doctors and patients.
- Innovation
- Transparency
- Scientific Rigour
- Speed of Development
- Effective Solutions
- Responsibility
Quality and safety. The guarantee of the highest quality standards
We work every day to ensure the highest quality standards for our customers. All our production processes comply with the UNI EN ISO 13485 certification for the production of medical devices and the UNI EN ISO 22716 certification for good manufacturing practices for cosmetics
The new concept of medical peeling
The new era of needle-free cellular regeneration and biorevitalization, for all skin types and all areas of the face and body. A complete line consisting of the innovative, patent-pending two-phase peels Nebula | ACTO2, Nebula | ACTO2 Orion, and the RH VIRGO post-treatment cream
Fast processing times
No photosensitivity phenomena
Suitable for all skin types
A valid support for acne treatment
Nebula | ACTO2

Areas of intervention:
- Acne in the acute phase, comedonal acne and post-acne
- Skin pigmentation
- Skin blemishes
- Biorevitalization
Efficacy studies

Keratolytic effect
Tests with competing products highlight the superior exfoliating power of Nebula | ACTO2 when compared to products with a higher concentration of acids. The graph shows how the stratum corneum removed after treatment is up to 12% thinner.

Dryness
Dryness is directly proportional to a product's keratolytic action. Increased dryness therefore indicates greater exfoliation of the stratum corneum. Nebula | ACTO2 demonstrated a 10% increase in skin dryness compared to other products with a higher percentage of acids in the formula.
Side effects
Tests with competing products highlight the superior exfoliating power of Nebula | ACTO2 when compared to products with a higher concentration of acids. The graph shows how the stratum corneum removed after treatment is up to 12% thinner.



The Nebula ACTO2 product has been shown to significantly reduce IL-1α at tested concentrations of 1.0 and 0.5 mg/ml (with a reduction of 14.4% and 13.7%, respectively, compared to no treatment).

The competitor product, at the concentrations tested, does not prove capable of significantly reducing IL-1α levels.

Interleukin-1α (IL-1α) is constitutively produced in large quantities by keratinocytes: under normal conditions, it remains stored within them, while damage or various stimuli can trigger its release. The primary role of IL-1α is to maintain the integrity of the skin's barrier function by preventing the entry of pathogenic microorganisms into the body, so its release indicates a significant inflammatory response. Comparison tests with a competing product show that Nebula | ACTO2 is able to significantly reduce IL-1α production by approximately 15%, demonstrating a soothing effect.
Choose the best formula for your patient

Nebula | ACTO2
Superficial chemical peel that acts on the stratum corneum and granulosum of the epidermis to treat mild acne lesions (comedones) as well as superficial scars. The blend of acids providesgentle exfoliation and adepigmenting effect for the treatment of mild discoloration. Removing the most damaged outer layers promotes cell renewal, reducing wrinkles, superficial scars, and skin blemishes.
WHO IS IT RECOMMENDED FOR?
This treatment is recommended for young skin. It's ideal for treating sensitive skin.

Nebula | ACTO2 Orion
A chemical peel with a high concentration of trichloroacetic acid that acts on the entire thickness of the epidermis, aimed at treating moderate to severe acne lesions (papules, pustules, nodules, and cysts) and deep scarring. The blend of acids providesintense exfoliation while simultaneously depigmenting the skin for more severe discoloration. It promotes cell renewal, reducing wrinkles, medium-to-superficial scars, and dark spots.
WHO IS IT RECOMMENDED FOR?
This treatment is recommended for mature skin.

RH Virgo
Dermatologically tested on sensitive skin, RH VIRGO is a post-treatment cream that helps soothe and protect the skin;
it absorbs quickly and has a pleasant texture, without any fragrance.
Active ingredients
The RH Virgo formulation contains:
- Perfluorodecalin
- Plankton extract
- Avocado oil
- Shea butter
- Vitamin E
- Sunscreens
HOW IT WORKS
VIRGO is an emulsion specially developed for post-treatment with the Nebula ACTO2 peel. Use morning and evening on treated areas, massaging until completely absorbed. It is also perfect for normal and combination skin.
Counteracts chronoaging
Counteracts photoaging
Counteracts hyperpigmentation
Fights fine wrinkles
Revitalizes the dermis and epidermis
Illuminating action
Anti-acne action
Double exfoliating and regenerating action
Areas to be treated

Face

Neck

Hands

Décolleté

Discover
needle-free revitalization
A new era for your patients
- Without needles
- Painless
- Rapid absorption
- It leaves no marks
- No frost
- Seasonal: the product can be applied all year round
Nebula Results | ACTO2
Nebula | ACTO2 Orion

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Other products

Skinfiller
Discover our Opéra range: facial fillers, lip fillers and body fillers, class III medical devices designed to reshape and redefine volumes without surgery, obtaining an immediate and long-lasting effect.

Skinbooster
Opèra REV Skinbooster is a line of biorevitalizing fillers designed to combat skin aging. Its advanced formula improves skin tone, reduces wrinkles, and combats cellular depletion.

Technical Care
The line of chemical peels for professionals, offered in different concentrations and formulations specifically designed to meet the needs of any skin type.

We work alongside doctors every day to offer safe and effective medical devices and aesthetic medicine products
Info
Products
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Operation financed by the POR FESR Tuscany 2014-2020
ACTION 3.1.1. sub-action 3.1.1a3)
“Aid aimed at containing and combating the COVID-19 epidemiological emergency”
“Tuscany Investment Fund – investment aid”
VIDA2020 PURCHASE OF PLANTS AND STOCKS
Financial support assigned: 100,000

This site is intended solely for informational purposes and is intended for healthcare professionals only. The information provided here should not be used as a substitute for medical advice or recommendations from healthcare professionals. It is not appropriate to use this information for self-diagnosis or self-treatment without first consulting a qualified healthcare provider.
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